Canadian Cancer Research Alliance

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Translational Research

To translate research findings into clinical practice, the Canadian Partnership Against Cancer is collaborating with the Terry Fox Research Institute on the Pan-Canadian Cancer Biomarker Initiative. The work’s focus is practical: to identify emerging technologies that can improve early detection and treatment methods using biomarkers, which are biochemical features that indicate the progress of disease or the effects of therapy.

The initiative focuses on five types of cancer — breast, leukemia and lymphoma, lung, ovarian and prostate. The most prominent undertaking so far is the Early Lung Cancer Detection Study. This study explores the use of questionnaires, a spirometry breathing test and a blood biomarker test to evaluate the effectiveness of identifying individuals at high risk of developing lung cancer. The aim is to identify Canadians who might benefit from more in-depth examination using spiral computed tomography (CT) scanning — a more sensitive, costlier test being studied internationally to determine its effectiveness in reducing mortality.

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